Elsevier

Journal of Electrocardiology

Volume 51, Issue 1, January–February 2018, Pages 92-98
Journal of Electrocardiology

Mapping of ventricular arrhythmias using a novel noninvasive epicardial and endocardial electrophysiology system

https://doi.org/10.1016/j.jelectrocard.2017.07.018Get rights and content
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open access

Highlights

  • Macro-reentrant circuits of scar-related VT can be visualized using a novel non-invasive electrophysiology system.

  • In patients without myocardial scar and inducible polymorphic VT/VF, only rotor activity and multiple wavelets were observed.

  • Use of the novel non-invasive electrophysiology system may help identify the optimal ablation strategy.

Abstract

Introduction

The aim of this study was to assess the use of a novel noninvasive epicardial and endocardial electrophysiology system (NEEES) for mapping of ventricular arrhythmias.

Methods

Eight patients (2 females, mean age 50 ± 17 years) with ischemic (n = 3) and nonischemic (n = 5) cardiomyopathy and inducible ventricular arrhythmias during electrophysiology study were enrolled. Noninvasive mapping of ventricular arrhythmias was performed using the NEEES based on body-surface electrocardiograms and computed tomography imaging data. Arrhythmia patterns were analyzed using noninvasive phase mapping.

Results

Macro-reentrant VT circuits were observed in 3 ischemic and 1 nonischemic cardiomyopathy patient, respectively. In the remaining 4 patients, phase mapping revealed relatively stable rotor activity and multiple wavelets.

Conclusions

Noninvasive cardiac mapping was able to visualize the macro-reentrant circuits in patients with scar-related VT. In patients without myocardial scar only polymorphic VT or VF was inducible, and rotor activity and multiple wavelets were observed.

Abbreviations

NEEES
noninvasive epicardial and endocardial electrophysiology system
VT
ventricular tachycardia
VF
ventricular fibrillation
ICD
implantable cardioverter-defibrillator
ICM
ischemic cardiomyopathy
HCM
hypertrophic cardiomyopathy
BrS
Brugada syndrome
CT
computed tomography
TTE
transthoracic echocardiography
LV
left ventricle
MRI
magnetic resonance imaging
EG
electrogram
PhS
phase singularity
RV
right ventricle
CL
cycle length
RVOT
right ventricular outflow tract

Keywords

Noninvasive cardiac mapping
Ventricular arrhythmias
Rotor activity
Multiple wavelets

Cited by (0)

Conflict of interest: V. Kalinin owns stock in EP Solutions SA. A. Tsyganov and M. Chmelevsky are consultants to EP Solutions SA. E. Wissner holds stock options and serves on the scientific advisory board of EP Solution SA.

1

Both authors contributed equally to the manuscript.