Journal of Electrocardiology
Volume 43, Issue 1 , Pages 15-24 , January 2010

Beat-to-beat interplay of heart rate, ventricular depolarization, and repolarization

  • György Kozmann, DSc

      Affiliations

    • Department of Electrical Engineering and Information Systems, University of Pannonia, Veszprém, Hungary
    • Department of Biomedical Engineering, Research Institute for Technical Physics and Materials Science of the Hungarian Academy of Sciences, Budapest, Hungary
    • Corresponding Author InformationCorresponding author. Department of Electrical Engineering and Information Systems, University of Pannonia, H-8201 P.O. Box 158, Veszprém, Hungary.
  • ,
  • Kristóf Haraszti, MSc

      Affiliations

    • Department of Biomedical Engineering, Research Institute for Technical Physics and Materials Science of the Hungarian Academy of Sciences, Budapest, Hungary
    • IQSYS Computing, member of Hungarian Telekom Group, Budapest, Hungary
  • ,
  • István Préda, MD, DSc

      Affiliations

    • Department of Cardiology, State Health Center, Budapest, Hungary
    • Cardiovascular Center, Semmelweis University, Budapest, Hungary

Received 23 September 2008

References 

  1. Kléber AG, Rudy Y. Basic mechanisms of cardiac impulse propagation and associated arrhythmias. Physiol Rev. 2004;84:431
  2. Goldberger JJ, Cain ME, Hohnloser SH, et al. American Heart Association; American College of Cardiology Foundation; Heart Rhythm Society. American Heart Association/American College of Cardiology Foundation/Heart Rhythm Society scientific statement on noninvasive risk stratification techniques for identifying patients at risk for sudden cardiac death: a scientific statement from the American Heart Association Council on Clinical Cardiology Committee on Electrocardiography and Arrhythmias and Council on Epidemiology and Prevention. Circulation. 2008;118:1497
  3. Berger RD, Kasper EK, Baughman KL, Marban E, Calkins H, Tomaselli GF. Beat-to-beat QT interval variability: novel evidence for repolarization lability in ischemic and nonischemic dilated cardiomyopathy. Circulation. 1997;96:1557
  4. Atiga WL, Calkins H, Lawrence JH, Tomaselli GF, Smith JM, Berger RD. Beat-to-beat repolarization lability identifies patients at risk for sudden cardiac death. J Cardiovasc Electrophysiol. 1998;9:899
  5. Burattini L, Zareba W. Time-domain analysis of beat-to-beat variability of repolarization morphology in patients with ischemic cardiomyopathy. J Electrocardiol. 1999;32(Suppl):166
  6. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation. 1996;93:1043
  7. Kreuz J, Lickfett LM, Schwab JO. Modern noninvasive risk stratification in primary prevention of sudden cardiac death. J Interv Card Electrophysiol. 2008;23:23
  8. Couderc JP, Zareba W, Burattini L, Moss AJ. Beat-to-Beat repolarization variability in LQTS patients with the SCN5A sodium channel gene mutation. Pacing Clin Electrophysiol. 1999;22:158
  9. Bloomfield DM, Steinman RC, Namerow PB, et al. Microvolt T-wave alternans distinguishes between patients likely and patients not likely to benefit from implanted cardiac defibrillator therapy: a solution to the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II conundrum. Circulation. 2004;110:1885
  10. Weiss JN, Qu Z, Chen PS, et al. The dynamics of cardiac fibrillation. Circulation. 2005;112:1232
  11. Abildskov JA, Evans AK, Lux RL, Burgess MJ. Ventricular repolarization properties and QRST area in cardiac electrograms. Am J Physiol. 1980;239:H227
  12. Hubley-Kozey CL, Mitchell LB, Gardner MJ, et al. Spatial features in body-surface potential maps can identify patients with a history of sustained ventricular tachycardia. Circulation. 1995;92:1825
  13. Plonsey R. A contemporary view of the ventricular gradient of Wilson. J Electrocardiol. 1979;12:337
  14. Geselowitz DB. The ventricular gradient revisited: relation to the area under the action potential. IEEE Trans Biomed Eng. 1983;30:76
  15. Cuppen JJ, van Oosterom A. Model studies with the inversely calculated isochrones of ventricular depolarization. IEEE Trans Biomed Eng. 1984;31:652
  16. van Oosterom A. Solidifying the solid angle. J Electrocardiol. 2002;35(Suppl):181
  17. Hoekema R, Uijen GJ, Stilli D, van Oosterom A. Lead system transformation of body surface map data. J Electrocardiol. 1998;31:71
  18. Khaddoumi B, Rix H, Meste O, Fereniec M, Maniewski R. Body surface ECG signal shape dispersion. IEEE Trans Biomed Eng. 2006;53(12 Pt 1):2491
  19. Lux RL, Smith CR, Wyatt RF, Abildskov JA. Limited lead selection for estimation of body surface potential maps in electrocardiography. IEEE Trans Biomed Eng. 1978;25:270
  20. Lux RL, Evans AK, Burgess MJ, Wyatt RF, Abildskov JA. Redundancy reduction for improved display and analysis of body surface potential maps. I. Spatial compression. Circ Res. 1981;49:186
  21. Abildskov JA, Green LS, Lux RL. Detection of disparate ventricular repolarization by means of the body surface electrocardiogram. In:  Zipes DP,  Jalife J editor. Cardiac electrophysiology and arrhythmias. New York, NY: Grune & Stratton; 1985;p. 495
  22. Yasuma F, Hayano J. Respiratory sinus arrhythmia: why does the heartbeat synchronize with respiratory rhythm?. Chest. 2004;125:683
  23. Hayano J, Yasuma F, Okada A, Mukai S, Fujinami T. Respiratory sinus arrhythmia. A phenomenon improving pulmonary gas exchange and circulatory efficiency. Circulation. 1996;94:842
  24. Grossman P, Taylor EW. Toward understanding respiratory sinus arrhythmia: relations to cardiac vagal tone, evolution and biobehavioral functions. Biol Psychol. 2007;74:263
  25. Sunagawa K, Maughan WL, Sagawa K. Optimal arterial resistance for the maximal stroke work studied in isolated canine left ventricle. Circ Res. 1985;56:586
  26. Asanoi H, Sasayama S, Kameyama T. Ventriculoarterial coupling in normal and failing heart in humans. Circ Res. 1989;65:483
  27. Miyano H, Nakayama Y, Shishido T, et al. Dynamic sympathetic regulation of left ventricular contractility studied in the isolated canine heart. Am J Physiol. 1998;275(2 Pt 2):H400
  28. Gepstein L, Hayam G, Ben-Haim SA. Activation-repolarization coupling in the normal swine endocardium. Circulation. 1997;96:4036
  29. Yue AM, Betts TR, Roberts PR, Morgan JM. Global dynamic coupling of activation and repolarization in the human ventricle. Circulation. 2005;112:2592
  30. Kozmann G, Haraszti K. Importance of body surface potential field representation fidelity: analysis of beat-to-beat repolarization measurements. Anadolu Kardiyol Derg. 2007;7(Suppl 1):5

PII: S0022-0736(09)00374-4

doi: 10.1016/j.jelectrocard.2009.08.003

Journal of Electrocardiology
Volume 43, Issue 1 , Pages 15-24 , January 2010