Journal of Electrocardiology
Volume 36 , Pages 127-132 , December 2003

The use of calculated epicardial potentials improves significantly the sensitivity of a diagnostic algorithm in the detection of acute myocardial infarction

  • César Navarro, PhD

      Affiliations

    • Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, Ireland, Northern Ireland
    • ,
  • Colum Owens, MRCP

      Affiliations

    • Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, Ireland, Northern Ireland
    • Corresponding Author InformationReprint requests: Colum Owens, MRCP, Regional Medical Cardiology Centre, Royal Victoria Hospital, Grosvenor Rd, Belfast, Ireland, Northern Ireland, BT12 6BA
    • ,
  • John Riddell, MRCP

      Affiliations

    • Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, Ireland, Northern Ireland
    • ,
  • Anthony McClelland, MRCP

      Affiliations

    • Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, Ireland, Northern Ireland
    • ,
  • John McC Anderson, Dphil

      Affiliations

    • University of Ulster at Jordanstown, Belfast, Ireland, Northern Ireland
    • ,
  • Omar Escalona, PhD

      Affiliations

    • University of Ulster at Jordanstown, Belfast, Ireland, Northern Ireland
    • ,
  • Colin Turner, PhD

      Affiliations

    • University of Ulster at Jordanstown, Belfast, Ireland, Northern Ireland
    • ,
  • Jennifer Adgey, MD (FACC)

      Affiliations

    • Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, Ireland, Northern Ireland

References 

  1. Fibrinolytic Therapy Trialists’ (FTT) Collaborative Group . Indications for fibrinolytic therapy in suspected acute myocardial infarction (Collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients). Lancet. 1994;343:311
  2. Gruppo Italiano per lo studio della streptochinasi nell’infarto miocardico (GISSI) . Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet. 1986;1:397
  3. ISIS-2 (Second International Study Of Infarct Survival) Collaborative Group . Randomised trial of intravenous streptokinase, oral aspirin, both or neither among 17187 cases of suspected acute myocardial infarction (ISIS-2). Lancet. 1988;2:349
  4. Fisch C. In:  Fisch C editors. The Clinical electrocardiogram (Sensitivity and specificity). New York, NY: Elsevier; 1997;p. 71
  5. Roberts R, Fromm R. Management of acute coronary syndromes based on risk stratification by biochemical markers. An idea whose time has come. Circulation. 1998;98:1831
  6. McMechan SR, MacKenzie G, Allen J, et al.  Body Surface ECG potential maps in acute myocardial infarction. J Electrocardiol. 1995;28(suppl):184
  7. Menown IB, Patterson RS, MacKenzie G, et al.  Body surface map models for early diagnosis of acute myocardial infarction. J Electrocardiol. 1998;31(suppl):180
  8. McClelland AJ, Owens CG, Menown IB, et al.  Comparison of the 80-lead body surface map to physician and 12-lead electrocardiogram in detection of acute myocardial infarction. Am J Cardiol. 2003; (in press)
  9. MacLeod RS, Brooks DH. Recent progress in inverse problems in electrocardiology. IEEE Eng Med Biol Mag. 1998;17:73
  10. Rudy Y, Messinger-Rapport BJ. The inverse problem in electrocardiography (Solutions in terms of epicardial potentials). Crit Rev Biomed Eng. 1988;16:215
  11. Messinger-Rapport BJ, Rudy Y. The inverse problem in electrocardiography (A model study of the effects of geometry and conductivity parameters on the reconstruction of epicardial potentials). IEEE Trans Biomed Eng. 1986;33:667
  12. Chang Y, Coddington P, Hutchens K. The NPAC/OLDA visible human viewer. Adelaide, Australia: Computer Science Department, Adelaide University; 1999; www.dhpc.adelaide.edu.au/projects/vishuman2/ Accessed 26th July
  13. Yamashita Y, Takahashi T. Use of the finite element method to determine epicardial from body surface potentials under a realistic torso model. IEEE Trans Biomed Eng. 1984;31:611
  14. Johnston PR, Gulrajani RM. A new method for regularization parameter determination in the inverse problem of electrocardiography. IEEE Trans Biomed Eng. 1997;44:19
  15. Johnston PR, Gulrajani RM. Selecting the corner in the L-curve approach to Tikhonov regularization. IEEE Trans Biomed Eng. 2000;47:1293
  16. Macfarlane PW. Minnesota coding and the prevalence of ECG abnormalities. Heart. 2000;84:582
  17. Menown IB, Allen J, Anderson JMC. Early diagnosis of right ventricular or posterior infarction associated with inferior wall left ventricular acute myocardial infarction. Am J Cardiol. 2000;85:934
  18. Riddell JW, Smith BA, Menown IB, et al.  Body Surface Mapping in Ischemic Heart Disease. W and G Belfast: Baird Publications; 2001;
  19. Maynard S. In: Use of body surface mapping to aid the diagnosis of myocardial infarction and ischaemia. Faculty of Medicine, Queens University of Belfast; 2002;p. 124; Doctoral Thesis
  20. Serinagaoglu Y, MacLeod RS, Yilmaz B, et al.  Multielectrode venous catheter mapping as a high quality constraint for electrocardiographic inverse solution. J Electrocardiol. 2002;35(suppl):65

☆ This work was supported by research fellowships from the Research and Development of the Northern Ireland Health and Social services Agency and the Frances and Augustus Newman Foundation.

PII: S0022-0736(03)00124-9

doi: 10.1016/j.jelectrocard.2003.09.036

Journal of Electrocardiology
Volume 36 , Pages 127-132 , December 2003

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