Journal of Electrocardiology
Volume 36 , Pages 7-12 , December 2003

Mechanisms of ST change in partial thickness ischemia

  • David Kilpatrick, MD (FRACP, MRCP)

      Affiliations

    • University of Tasmania, Hobart, Australia
    • Corresponding Author InformationReprint requests: David Kilpatrick, Medicine, University of Tasmania, 43 Collins St, Hobart7000, Australia
    • ,
  • Peter R. Johnston, PhD, BSc

      Affiliations

    • School of Science, Griffith University, Queensland, Australia
    • ,
  • D.S. Li, MD, PhD

      Affiliations

    • University of Tasmania, Hobart, Australia
    • School of Science, Griffith University, Queensland, Australia

References 

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  2. Toyoshima H, Ekmekci A, Flamm E, et al.  Angina pectoris VII (The nature of ST depression in acute myocardial ischaemia). Am J Cardiol. 1964;13:498
  3. Holland RP, Brooks H. Precordial and epicardial surface potentials during myocardial ischemia in the pig (A theoretical and experimental analysis of the TQ and ST segments). Circ Res. 1975;37:471
  4. Holland RP, Brooks H. TQ-ST segment mapping (Critical review and analysis of current concepts). Am J Cardiol. 1977;40:110
  5. Bayley RH. The electrocardiographic effects of injury at the endocardial surface of the left ventricle. Am Heart J. 1946;31:677
  6. Li RA, Leppo M, Miki T, et al.  Molecular basis of electrocardiographic ST-segment elevation. Circ Res. 2000;87:837
  7. Kleber AG, Janse MJ, van Capelle FJL, et al.  Mechanism and time course of S-T and T-Q segment changes during acute regional myocardial ischemia in the pig heart determined by extracellular and intracellular recordings. Circ Res. 1978;42:603
  8. Samson WE, Scher AM. Mechanism of S-T segment alteration during acute myocardial injury. Circ Res. 1960;8:780
  9. Otto HL. The ventricular electrocardiogram (An experimental study). Arch Int Med. 1929;43:335
  10. Dunn R, Freedman B, Bailey I, et al.  Localization of coronary artery disease with exercise electrocardiography (Correlation with thallium-201 myocardial perfusion scanning). Am J Cardiol. 1981;48:837
  11. Mark DB, Hlatky MA, Lee KL. Localizing coronary artery obstructions with the exercise treadmill test. Ann Intern Med. 1987;106:53
  12. Ekeda K, Kubota L, Igarashi A, et al.  Detection of local abnormalities in ventricular activation sequence by body surface isochrome mapping in patients with previous myocardial infarction. Circulation. 1985;72:801
  13. Wilson FN, Macleod AG, Barker PS. The distribution of the currents of action and injury displayed by heart muscle and other excitable tissues. Univ Mich Studies Sci Ser. 1933;10:1
  14. Tung L. A Bi-domain model for describing ischaemic myocardial D-C potentials. 1978; Doctoral thesis, Massachusetts Institute of Technology, June
  15. Li D, Li CY, Yong AC, et al.  Source of electrocardiographic ST changes in subendocardial ischemia. Circ Res. 1998;82:957
  16. Li D, Li CY, Yong AC, et al.  Epicardial ST depression in acute myocardial infarction. Circ Res. 1999;85:959
  17. Johnston PR, Kilpatrick D, Li CY. The importance of anisotropy in modelling ST segment shift in subendocardial ischaemia. IEEE Trans Biomed Eng. 2001;48:1366
  18. Johnston PR, Kilpatrick D. The effect of conductivity values on ST segment shift in subendocardial ischaemia. IEEE Trans Biomed Eng. 2003;50:150
  19. Li D, Yong AC, Kilpatrick D. Validation of a subendocardial ischaemic sheep model by intracoronary fluorescent microspheres. Clin Exp Pharm Physiol. 1996;23:111
  20. Schmitt OH. Biological information processing using the concept of interpenetrating domains. In:  Leibovic KN editors. Information Processing in the Nervous System. New York: Springer-Verlag; 1969;p. 325
  21. Clerc L. Directional differences of impulse spread in trabecular muscle from mammalian heart. J Physiol. 1976;255:335
  22. Roberts DE, Hersh LT, Scher AM. Influence of cardiac fiber orientation on wavefront voltage, conduction velocity and tissue resistivity in the dog. Circ Res. 1979;44:70s1
  23. Roberts DE, Scher AM. Effects of tissue anisotropy on extracellular potential fields in canine myocardium in situ. Circ Res. 1982;50:342

PII: S0022-0736(03)00090-6

doi: 10.1016/j.jelectrocard.2003.09.002

Journal of Electrocardiology
Volume 36 , Pages 7-12 , December 2003

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